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Contents: April 2015, Volume 2015, Issue 1   [Index by Author]       Educational Sessions        Bench to Bedside and Back Again: Biology and Therapy of ALK and BRAF Cancers        Cancer Drug Discovery 2015: Challenges and Opportunities for Academia and Industry        Improving Cancer Drug Bioavailability by Use of Controlled Delivery and Release        Intravital Imaging in Animal Models of Cancer        Liquid Biopsy Biomarkers        Pediatric Low-grade Gliomas: Silent but Still Deadly        Population Screening for Inherited Breast and Ovarian Cancers: Are We There Yet?        Role of Non-Coding RNAs in Cancer        Therapeutic Targeting and Monitoring Tumor Microenvironments        Tumor Immunology and Immunotherapy for the Non-immunologist      Methods Workshops        Cell Line Authentication: Improving the Reproducibility and Translatability of Preclinical Cancer Research        Design and Method Workshop for Clinical Trials and Population Studies, Part 2: Design Considerations for Expanding the Success of Immunotherapy Trials        How and When to Use Chemical Probes        Novel Platforms for Early Detection of Malignancies        Organoids      Tumor Heterogeneity and Evolution      Novel Platforms for Early Detection of Malignancies

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Educational Sessions

Bench to Bedside and Back Again: Biology and Therapy of ALK and BRAF Cancers

Ruth H. Palmer

ALK biology in health and disease
Am Assoc Cancer Res Educ Book 2015: 3-8. doi: 10.1158/AACR.EDB-15-8746. [Full Text] [PDF]  

Cancer Drug Discovery 2015: Challenges and Opportunities for Academia and Industry

Allan M. Jordan

Collaborating with industry to find chemical hits versus difficult targets
Am Assoc Cancer Res Educ Book 2015: 11-16. doi: 10.1158/AACR.EDB-15-8389. [Full Text] [PDF]  

Improving Cancer Drug Bioavailability by Use of Controlled Delivery and Release

Mark W. Dewhirst and Chen-Ting Lee

Thermally enhanced liposomal drug delivery
Am Assoc Cancer Res Educ Book 2015: 19-26. doi: 10.1158/AACR.EDB-15-8186. [Full Text] [PDF]  

Dennis E. Hallahan

Improving cancer drug bioavailability by use of controlled delivery and release
Am Assoc Cancer Res Educ Book 2015: 27-28. doi: 10.1158/AACR.EDB-15-8182. [Full Text] [PDF]  

Intravital Imaging in Animal Models of Cancer

Claire Vennin and Paul Timpson

Intravital microscopy of cancer: New insights into the spatiotemporal dynamics of the disease
Am Assoc Cancer Res Educ Book 2015: 31-36. doi: 10.1158/AACR.EDB-15-8637. [Full Text] [PDF]  

Michiyuki Matsuda

Intravital imaging of mice expressing Förster resonance energy transfer (FRET) biosensors
Am Assoc Cancer Res Educ Book 2015: 37-42. doi: 10.1158/AACR.EDB-15-8642. [Full Text] [PDF]  

Liquid Biopsy Biomarkers

Alain R. Thierry

Circulating DNA and cancer
Am Assoc Cancer Res Educ Book 2015: 45-50. doi: 10.1158/AACR.EDB-15-7973. [Full Text] [PDF]  

Pediatric Low-grade Gliomas: Silent but Still Deadly

David T. W. Jones

Pediatric low-grade glioma: An overview of biology and molecular diagnostic/prognostic markers
Am Assoc Cancer Res Educ Book 2015: 53-58. doi: 10.1158/AACR.EDB-15-9738. [Full Text] [PDF]  

Sabine Mueller

Past and future challenges for the clinical care of children with low-grade gliomas
Am Assoc Cancer Res Educ Book 2015: 59-62. doi: 10.1158/AACR.EDB-15-9740. [Full Text] [PDF]  

Population Screening for Inherited Breast and Ovarian Cancers: Are We There Yet?

Patricia Ashton-Prolla

Population-based strategy for breast cancer screening in Brazil
Am Assoc Cancer Res Educ Book 2015: 65-68. doi: 10.1158/AACR.EDB-15-8004. [Full Text] [PDF]  

Role of Non-Coding RNAs in Cancer

Srivatsava Naidu, Lei Shi, and Michela Garofalo

MicroRNAs in lung tumorigenesis and chemoresistance
Am Assoc Cancer Res Educ Book 2015: 71-74. doi: 10.1158/AACR.EDB-15-7984. [Full Text] [PDF]  

Therapeutic Targeting and Monitoring Tumor Microenvironments

Jacob L. Austin-Breneman, Hong Jiang, Zachary A. Cooper, and Jennifer A. Wargo

Therapeutic targeting and monitoring tumor immunity in melanoma
Am Assoc Cancer Res Educ Book 2015: 77-82. doi: 10.1158/AACR.EDB-15-8781. [Full Text] [PDF]  

Tumor Immunology and Immunotherapy for the Non-immunologist

Todd A. Fehniger

Natural killer cells: Basic biology and immunotherapy potential
Am Assoc Cancer Res Educ Book 2015: 85-88. doi: 10.1158/AACR.EDB-15-8030. [Full Text] [PDF]  

Jeffrey S. Weber

Cancer immunology for the non-immunologist
Am Assoc Cancer Res Educ Book 2015: 89-92. doi: 10.1158/AACR.EDB-15-7955. [Full Text] [PDF]  

Methods Workshops

Cell Line Authentication: Improving the Reproducibility and Translatability of Preclinical Cancer Research

Leonard P. Freedman and Vivian Siegel

Cell line authentication to improve preclinical cancer research: Policies and training
Am Assoc Cancer Res Educ Book 2015: 95-98. doi: 10.1158/AACR.EDB-15-9039. [Full Text] [PDF]  

Stephen P. Ethier and Richard M. Neve

Cell line authentication to improve preclinical cancer research: Methods in cell line authentication, quality control, and annotation
Am Assoc Cancer Res Educ Book 2015: 99-104. doi: 10.1158/AACR.EDB-15-9041. [Full Text] [PDF]  

Design and Method Workshop for Clinical Trials and Population Studies, Part 2: Design Considerations for Expanding the Success of Immunotherapy Trials

Tai-Tsang Chen

Statistical issues on the design and analysis of cancer immunotherapy trials
Am Assoc Cancer Res Educ Book 2015: 107-110. doi: 10.1158/AACR.EDB-15-9835. [Full Text] [PDF]  

How and When to Use Chemical Probes

Evelyne Lima-Fernandes, Dalia Barsyte-Lovejoy, and Cheryl H. Arrowsmith

Epigenetic chemical probes to identify therapeutic targets in oncology
Am Assoc Cancer Res Educ Book 2015: 113-118. doi: 10.1158/AACR.EDB-15-8496. [Full Text] [PDF]  

Novel Platforms for Early Detection of Malignancies

Paul D. Lampe

High-density arrays to profile circulating biomarkers
Am Assoc Cancer Res Educ Book 2015: 121-124. doi: 10.1158/AACR.EDB-15-8477. [Full Text] [PDF]  

John K. Field and Michael W. Marcus

Risk prediction models in lung cancer: The methodology for identifying high risk individuals for future lung cancer computed tomography (CT) screening programs
Am Assoc Cancer Res Educ Book 2015: 125-132. doi: 10.1158/AACR.EDB-15-8767. [Full Text] [PDF]  

Organoids

Samuel D. Kaffenberger, Dong Gao, and Yu Chen

Organoid cultures from benign and malignant prostate epithelium
Am Assoc Cancer Res Educ Book 2015: 135-138. doi: 10.1158/AACR.EDB-15-9176. [Full Text] [PDF]  

Tumor Heterogeneity and Evolution

Andriy Marusyk, Michalina Janiszewska, and Doris Tabassum

Determinants of phenotypic intratumor heterogeneity: Integrative approach
Am Assoc Cancer Res Educ Book 2015: 141-145. doi: 10.1158/AACR.EDB-15-8042. [Full Text] [PDF]  

Novel Platforms for Early Detection of Malignancies

Sam Hanash

Circulating protein biomarker discovery strategies using mass spectrometry for cancer early detection applications
Am Assoc Cancer Res Educ Book 2015: 147-153. doi: 10.1158/AACR.EDB-15-8483. [Full Text] [PDF]  

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